General Cell Lines and Cell Cultures
Eurofins Discoverx KILR HT-1080 Cell Pool, 2 vials. (97-1031P043)
The KILR HT-1080 cell pool is a stable, engineered target cell pool, which closely reflects the heterogeneous native protein expression of tumor environments, used to measure direct cell death mediated by immunooncology treatments (e.g. checkpoint modulators, bispecifics, CAR-T, etc.) via Antibody Dependent Cell-mediated Cytotoxicity (ADCC), Complement Dependent Cytotoxicity (CDC), and Antibody Dependent Cell Phagocytosis (ADCP). This product uses EFC technology. The cell pool is a heterogeneous population of HT-1080 cells that overexpress a ProLabel-tagged housekeeping gene. Upon effector cells-mediated cell lysis, ProLabel is released to the media, where EA in the detection kit produces an EFC signal proportional to the level of ProLabel released. This allows for calculation of percent lysis of the KILR cell pool. This stable cell pool is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/kilr.
ATCC CCF-STTG1; Astrocytoma; Human (Homo sapiens)
CCF-STTG1 is an astrocytic-like cell that was isolated from the brain of a White, 68-year-old, female patient with astrocytoma and can be used in neuroscience research. This cell line was deposited by BP Barna.
ATCC HL-60; Promyelocytic Leukemia; Human (Homo sapiens)
HL-60 cells are promyeoloblasts isolated from the peripheral blood by leukopheresis from a 36-year-old,White, female with acute promyelocytic leukemia. This cell line can be used in immune disorder and immunology research.
ATCC Aeromonas hydrophila
Aeromonas hydrophila strain LRA 3300 776 [API SA, DSM 6173] can be used as a quality control strain for API products.
ATCC Enterobacter cloacae; Strain 1000654
Enterobacter cloacae strain 1000654 is a whole-genome sequenced bacterium that was isolated from human urine. This strain is resistant to ertapenem and imipenem and was confirmed by PCR to contain the blaNDM gene. The strain can be used for antimicrobial resistance research, drug development, and infectious disease research.
ATCC HCT116-SLC25A14-KO-c11; Colorectal carcinoma; Human(Homo sapiens)
The HCT116-SLC25A14-KO-c11 cell line contains a 1 bp insertion in SLC25A14 gene and combined with the parental cell line and other HCT116 derivatives can be used in cancer drug screening.
ATCC Enterococcus faecium
This whole-genome sequenced strain of Enterococcus faecium was isolated from human feces. It is multidrug resistant and was confirmed by PCR to harbor the vanA gene. It has applications in antimicrobial resistance research and drug development.
ATCC Streptococcus gordonii; V288
This is a bacterial strain with applications as a transformation host. Explore the use of this strain in your molecular biology research.